Part,  Chapter, Paragraph

  1   II,     5.  1.  1|            exposure to certain gases/chemicals may also be influential.
  2   II,     5.  1.  1|          body”.~Biochemical factors: chemicals in the brain that control
  3   II,     5.  1.  1|           during development to some chemicals, such as methyl mercury,
  4   II,     5.  1.  1|           some pharmaceuticals. Some chemicals (e.g.: polychlorinated biphenyls (
  5   II,     5.  3.  4|            exposure to certain gases/chemicals may also be influential.
  6   II,     5.  5.  3|            and~· Biological factors: chemicals in the brain that control
  7   II,     5.  8.  2|                 due to inhalation of chemicals, gases, fumes or vapours ( J6 ~·
  8   II,     5.  9.  4|       cooking and heating, household chemicals, furnishings wall and floor
  9   II,     5. 12.  4|             potentially hepato-toxic chemicals in these alcoholic beverages.
 10   II,     9        |             the risks of exposure to chemicals, in the occupational, domestic
 11   II,     9        |          sites, endocrine disrupting chemicals, pesticides and solvents.~ ~
 12   II,     9        |            exposure to certain gases/chemicals may also be influential. ~ ~
 13   II,     9.  1.  2|              to endocrine disrupting chemicals. The high rate of hypospadias
 14   II,     9.  1.  2|             the risks of exposure to chemicals, in the occupational, domestic
 15   II,     9.  1.  2|          sites, endocrine disrupting chemicals, pesticides and solvents.~ ~
 16   II,     9.  3.  1|            exposure to certain gases/chemicals may also be influential. ~ ~
 17  III,    10.  1    |    estimations of the body burden of chemicals, combined exposures from
 18  III,    10.  1    |           environmental exposures to chemicals and other environmental
 19  III,    10.  2.  1|          during smoking, almost 4000 chemicals can be found in the smoke.~ ~
 20  III,    10.  2.  1|            and potentially hazardous chemicals within the European population.
 21  III,    10.  2.  4|   Authorisation and Restriction of~ ~Chemicals ~RNA~Ribonucleic Acid~TMA~
 22  III,    10.  2.  5|              For example exposure to chemicals during early fetal development
 23  III,    10.  2.  5|        substantial delays. About 200 chemicals are known to cause clinical
 24  III,    10.  2.  5|             testing, many additional chemicals have been shown to be neurotoxic
 25  III,    10.  2.  5|            The toxic effects of such chemicals in the developing human
 26  III,    10.  2.  5|            the great gaps in testing chemicals for developmental neuro-toxicity
 27  III,    10.  2.  5|              identified more than 50 chemicals causing cancer in adult
 28  III,    10.  2.  5|           concluded that exposure to chemicals with a mutagenic mode of
 29  III,    10.  2.  5|            to toxic and carcinogenic chemicals, biological pathogens and
 30  III,    10.  3.  1|            such as air pollution and chemicals. This may be particularly
 31  III,    10.  3.  2|            Mutagenic and Repro-toxic chemicals~DALY~Disability adjusted
 32  III,    10.  3.  2|              Commission~ECB~European Chemicals Bureau~ECHA~European Chemicals
 33  III,    10.  3.  2|       Chemicals Bureau~ECHA~European Chemicals Agency~EEA~European Environment
 34  III,    10.  3.  2|          International Conference on Chemicals Management~IPPC~Integrated
 35  III,    10.  3.  2|         Evaluation, Authorization of Chemicals Register~Rh~Rhodium~SAICM~
 36  III,    10.  3.  2|            Approach to international Chemicals~TDI~Tolerable Daily Intake~
 37  III,    10.  3.  2|          States~VOC~Volatile organic chemicals~WHO~World Health Organisation~
 38  III,    10.  3.  2|             10.3.2.1. Introduction~ ~Chemicals, natural and man-made, are
 39  III,    10.  3.  2|          between different groups of chemicals; industrial chemicals, agrochemicals (
 40  III,    10.  3.  2|             of chemicals; industrial chemicals, agrochemicals (e.g. fertilizers,
 41  III,    10.  3.  2|         mainly deals with industrial chemicals but in some instances reference
 42  III,    10.  3.  2|              the production of toxic chemicals has increased at almost
 43  III,    10.  3.  2|              The production of toxic chemicals has increased at almost
 44  III,    10.  3.  2|      Evaluation and Authorisation of Chemicals (REACH) is estimated to
 45  III,    10.  3.  2|             Emissions and release of chemicals are not only closely linked
 46  III,    10.  3.  2|               but also to the use of chemicals in downstream sectors and
 47  III,    10.  3.  2|              relevance of the use of chemicals is extremely difficult to
 48  III,    10.  3.  2|       climate change and exposure to chemicals that disrupt endocrine function
 49  III,    10.  3.  2|         Evaluation, Authorization of Chemicals), a uniform system for the
 50  III,    10.  3.  2|             management of industrial chemicals within the Union. The ultimate
 51  III,    10.  3.  2|              an increasing number of chemicals, often in complex mixtures
 52  III,    10.  3.  2|              the whole life cycle of chemicals. New risks from 'old' pollutants
 53  III,    10.  3.  2|              but also bears risks as chemicals can be released into the
 54  III,    10.  3.  2|        Fourth assessment (chapter on chemicals), and the EEA / Joint Research
 55  III,    10.  3.  2|    Commission Services.~ ~· European Chemicals Bureau http /. This webpage
 56  III,    10.  3.  2|              the Sound Management of Chemicals http / (will be transferred
 57  III,    10.  3.  2|            Approach to international Chemicals Management, Secretariat http
 58  III,    10.  3.  2|         organic pollutants ( ht UNEP Chemicals, Lead and cadmium ( ht The
 59  III,    10.  3.  2|             of activities related to chemicals; one of the latest is the
 60  III,    10.  3.  2|        Global Information Network on Chemicals (GINC), which still contains
 61  III,    10.  3.  2|              the future the European Chemicals Agency (ECHA) will be an
 62  III,    10.  3.  2| significantly to the global trade in chemicals, which increased by an average
 63  III,    10.  3.  2|             production of industrial chemicals increasing by 31% and GDP
 64  III,    10.  3.  2|              The production of toxic chemicals25 increased by 23.5%. The
 65  III,    10.  3.  2|            mutagenic and repro-toxic chemicals (CMR) - increased by 22% (
 66  III,    10.  3.  2|       production of toxic industrial chemicals in the EU25 in 2005, as
 67  III,    10.  3.  2|             for most of the flows of chemicals in today’s society, and
 68  III,    10.  3.  2|     Production volumes of industrial chemicals relative to GDP for EU Member
 69  III,    10.  3.  2|             2.3. Production of toxic chemicals in the EU. Source: Eurostat,
 70  III,    10.  3.  2|             led to major releases of chemicals into the environment, trans-boundary
 71  III,    10.  3.  2|         environmental concerns about chemicals that had not previously
 72  III,    10.  3.  2|            some associations between chemicals and human diseases/disorders.
 73  III,    10.  3.  2|           environmental exposures to chemicals and other environmental
 74  III,    10.  3.  2|          potential health effects of chemicals in human. Indeed, much of
 75  III,    10.  3.  2|              assessing the impact of chemicals on human health is that
 76  III,    10.  3.  2|       neurodevelopment; “Exposure to chemicals during early foetal development
 77  III,    10.  3.  2|      substantial delays. Another 200 chemicals are known to cause clinical
 78  III,    10.  3.  2|             testing, many additional chemicals have been shown to be neurotoxic
 79  III,    10.  3.  2|            The toxic effects of such chemicals in the developing human
 80  III,    10.  3.  2|            the great gaps in testing chemicals for developmental neurotoxicity
 81  III,    10.  3.  2|              identified more than 50 chemicals causing cancer in adult
 82  III,    10.  3.  2|           concluded that exposure to chemicals with a mutagenic mode of
 83  III,    10.  3.  2|            Carcinogens~ ~A number of chemicals are potentially carcinogenic.
 84  III,    10.  3.  2|        European citizen has man-made chemicals in his or her body. Bio-monitoring
 85  III,    10.  3.  2|         human exposure to persistent chemicals in the normal life situation
 86  III,    10.  3.  2|           handling and management of chemicals to protect both human health
 87  III,    10.  3.  2|               Emissions of hazardous chemicals from industrial installations
 88  III,    10.  3.  2|              mid-2005.~ ~The current chemicals legislation on the Registration,
 89  III,    10.  3.  2|      Evaluation and Authorisation of Chemicals (REACH) entered into force
 90  III,    10.  3.  2|            Approach to International Chemicals Management (UNEP, 2006),
 91  III,    10.  3.  2|      Procedure for Certain Hazardous Chemicals (UNEP and FAO, 1998), the
 92  III,    10.  3.  2|       Approach towards International Chemicals Management (SAICM) was adopted
 93  III,    10.  3.  2|          International Conference on Chemicals Management (ICCM) in Dubai
 94  III,    10.  3.  2|              the Sound Management of Chemicals. It provides a policy framework
 95  III,    10.  3.  2|           for ensuring that by 2020, chemicals are produced and used in
 96  III,    10.  3.  2|       handling, transport and use of chemicals.~ ~
 97  III,    10.  3.  2|               The safe management of chemicals requires the co-operation
 98  III,    10.  3.  2|      stewardship. But legislation on chemicals and legislative tools that
 99  III,    10.  3.  2|            protection from hazardous chemicals are often developed and
100  III,    10.  3.  2|         integrated approach to sound chemicals management would contain
101  III,    10.  3.  2|             to ensure that hazardous chemicals, products and processes
102  III,    10.  3.  2|            sustainable management of chemicals will contribute to reaching
103  III,    10.  3.  2|  Environmental Indicators Related to Chemicals http d; Annex http ~ ~Grandjean
104  III,    10.  3.  2|          neurotoxicity of industrial chemicals. Lancet 368, 2167-2178.~ ~
105  III,    10.  3.  2|              Pollution (RCEP, 2003): Chemicals in productssafeguarding
106  III,    10.  3.  2|            Approach to International Chemicals Management (SAICM). Available
107  III,    10.  3.  2|      Procedure for Certain Hazardous Chemicals. Available at: htt ~ ~UNEP
108  III,    10.  3.  2|            Available at: htt ~ ~UNEP Chemicals, Lead and cadmium (htt ~ ~
109  III,    10.  3.  2|      Classification and Labelling of Chemicals. Available at: htt ~ ~World
110  III,    10.  3.  2|          associated with exposure to chemicals. Geneva, World Health Organisation.
111  III,    10.  3.  4|         water systems with dangerous chemicals from storage, plants or
112  III,    10.  4.  1|         dioxide (SO2 ). In addition, chemicals such as polyaromatic hydrocarbons (
113  III,    10.  4.  1|              increase the release of chemicals from construction materials.
114  III,    10.  4.  1|        allergens from house animals. Chemicals like formaldehyde and benzene
115  III,    10.  4.  1|              construction materials, chemicals from treatment of furniture
116  III,    10.  4.  2|            arsenic, one of the first chemicals recognised as carcinogen,
117  III,    10.  4.  2|             marine transportation of chemicals over long distances may
118  III,    10.  4.  2|             areas far from where the chemicals were released. For example,
119  III,    10.  4.  2|         mercury and other persistent chemicals, impacting not only the
120  III,    10.  4.  2|           carcinogenic and untogenic chemicals, applicable to acrylamide
121  III,    10.  4.  2|        number of organica xenobiotic chemicals have been detected in human
122  III,    10.  4.  2|               The risk assessment of chemicals in food is a purely scientific
123  III,    10.  4.  3|             heavy metals, industrial chemicals, nitrates, pesticides and
124  III,    10.  4.  3|         Arsenic was one of the first chemicals recognised as a cause of
125  III,    10.  4.  3|              or fluoride, industrial chemicals, or agricultural chemicals
126  III,    10.  4.  3|           chemicals, or agricultural chemicals such as pesticides and nitrite.
127  III,    10.  4.  3|      Focusing on water contaminating chemicals, the European Commission
128  III,    10.  4.  3|          veterinary pharmaceuticals. Chemicals from industry, agriculture
129  III,    10.  4.  4|             for most of the flows of chemicals in today’s society as well
130  III,    10.  4.  5|            and inadequate storage of chemicals (see Figure 10.4.5.2.1;
131  III,    10.  4.  5|            instance on water, waste, chemicals, industrial pollution prevention,
132  III,    10.  4.  5|              the storage of obsolete chemicals covers more than 30 % of
133  III,    10.  4.  5|            measures on water, waste, chemicals, industrial pollution prevention,
134  III,    10.  5.  1|           and bacteria as well as by chemicals and heavy metals.~ ~Within
135  III,    10.  5.  1|    brownfields) in which a number of chemicals or heavy metals may be found (
136  III,    10.  5.  3|           such as noise or dangerous chemicals. However, it has become
137   IV,    12.  2    |            environment (carcinogenic chemicals). A new primary prevention
138   IV,    12.  2    |            exposures to carcinogenic chemicals or other determinants to
139   IV,    12.  4    |  Biotechnology; Safety of Cosmetics;~Chemicals; Innovation~ENV~Environmental
140   IV,    12.  4    |              directly or indirectly (chemicals, air pollution, deteriorated
141   IV,    12.  4    |          diseases.~ ~ECHA~ ~European Chemicals Agency (Helsinki, Finland) –
142   IV,    12.  4    |        regulation on the safe use of chemicals, No 1907/2006) and to ensure
143   IV,    12.  4    |             on questions relating to chemicals which fall under REACH~To
144   IV,    12.  4    |   registrants To make information on chemicals publicly accessible~EEA~ ~
145   IV,    12. 10    |        Immission Protection Law. The Chemicals Act will now be replaced
146   IV,    12. 10    |      production and use of hazardous chemicals (“the dirty dozen”, persistent
147   IV,    12. 10    |    administration and restriction of chemicals entered into force the 1st
148   IV,    12. 10    |             in force since June 2007~Chemicals Bills 2008~See www. ie and www. ie~
149   IV,    12. 10    |          export of certain dangerous chemicals~S.I. 317 of 2003 - pesticide
150  Key,   Ap5.  0.  0|            charter~charters~chemical~chemicals~chemotherapy~chickenpox~