5.9.6. Future Developments
Asthma is a significant burden, not only in terms of
health care costs and lost productivity but also of quality of life impairment.
Asthmatic symptoms deeply influence individual lifestyle: acute asthma episodes
are for many people somewhat unpredictable and can be more stressful than
events that can be anticipated and prepared for. Feeling that another asthma
episode could start at any time may cause a person to feel constantly anxious.
Aspects of having asthma such as using an inhaler or avoiding triggers, as well
as the asthma symptoms themselves, can make a person feel different and set
apart from other people. This is why Health Related Quality of Life (HRQoL) has
become a fundamental instrument for achieving a complete description of asthma,
focused not only on clinical data but also on the impact the disease and its
therapy as perceived by patients (Schipper et al, 1990). Quality of life
research has demonstrated the importance of adopting specific criteria
permitting the integration of the objective evaluation of asthma symptoms with
the subjective perceptions of the patient. The assessment of HRQoL in asthmatic
patients has been attracting an increasing interest during the last two
decades. Many questionnaires have been created to evaluate the impact of asthma
from the patients’ point of view (Baiardini et al, 2006). HRQoL is assessed by
means of validated questionnaires, that can be generic or specific: generic
tools can be used in all health conditions and allow the comparison of HRQoL of
patients affected by different diseases with healthy subjects, while specific
questionnaires focus on the aspects of health status relevant for patients with
a specific disease or clinical condition.
The importance of this point is confirmed by the
international guidelines for asthma: the Global Initiative for Asthma (GINA)
document (GINA, 2006). Global strategy for asthma management and prevention
considers HRQoL as a relevant issue for the search of healthcare intervention
and the choice of appropriate treatment (WHO, 1952).
GINA guidelines underline the importance of prevention
strategies in controlling symptoms and improving the quality of life in
asthmatic patients: measures for prevention of allergic sensitization, asthma
development and exacerbations should be implemented whenever possible. Allergic
sensitization can occur prenatally, but at present there are no strategies to
prevent allergic sensitization; the role of allergen-free diet for high risk
woman in pregnancy is still unclear, even if breastfeeding seems to protect
against the development of wheezing illnesses in early childhood. GINA is a
partner organization of the Global Alliance against chronic Respiratory Diseases
(GARD) (
Bousquet et al, 2006), a WHO initiative
aiming at facilitating the collaboration among existing programs regarding
chronic respiratory diseases. The participating organizations will develop a
new global approach towards prevention and control of chronic respiratory
diseases, with a particular emphasis on developing Countries.
For what concerns allergic rhinitis, the ARIA organization
(Allergic Rhinitis and its impact on Asthma), an organization, working in
partnership with WHO, has provided the first set of guidelines to be used
worldwide for what concerns treatment and evidence-based recommendations
(Bousquet et al, 2006). ARIA goals for both specialists and primary caregivers
are to improve the management of allergic rhinitis and to complement the GINA
guidelines, the gold standard for the management of asthma. ARIA highlights the
impact of allergic rhinitis on asthma, that are common comorbidities,
suggesting the concept “one airway, one disease”. Hopefully, ARIA guidelines
will improve a better understanding of the interactions between allergic
rhinitis and asthma, increase the awareness of the socio-economical impact of
rhinitis and make effective treatment for rhinitic symptoms available for every
patient in the world.