Part, Chapter, Paragraph
1 II, 5. 6.Acr| anti-inflammatory analgesics drugs~OA~Osteoarthritis~RA~Rheumatoid
2 II, 5. 6. 3| Definition~ ~Osteoarthritis (OA) is characterised by focal
3 II, 5. 6. 3| thickening of the capsule. OA can affect any joint, but
4 II, 5. 6. 3| estimate the prevalence of OA in different joint sites (
5 II, 5. 6. 3| preferred definition for OA includes both x-ray findings
6 II, 5. 6. 3| al, 1992). Progression of OA is accelerated by age, and
7 II, 5. 6. 3| disability associated with OA increases with progressive
8 II, 5. 6. 3| presenting to health care with OA by agreed criteria. An estimation
9 II, 5. 6. 3| prevalence of symptomatic knee OA was 2.3% compared to 17%
10 II, 5. 6. 3| radiologically defined knee OA (Spector et al, 1991).~ ~
11 II, 5. 6. 3| 1991).~ ~The prevalence of OA increases indefinitely with
12 II, 5. 6. 3| indefinitely with age as OA is not reversible (Figures
13 II, 5. 6. 3| 55 – 74 the prevalence of OA of the hand is 70%, foot
14 II, 5. 6. 3| of the hand is 70%, foot OA 40%, knee OA 10% and hip
15 II, 5. 6. 3| is 70%, foot OA 40%, knee OA 10% and hip OA 3% (Lawrence
16 II, 5. 6. 3| 40%, knee OA 10% and hip OA 3% (Lawrence et al, 1998).~ ~
17 II, 5. 6. 3| that can be attributed to OA (Symmons et al, 2003).~ ~
18 II, 5. 6. 3| 6.3. Prevalence of knee OA in Europe~ ~Figure 5.6.4a.
19 II, 5. 6. 3| Prevalence of radiographic OA by age A) Men~Figure 5.6.
20 II, 5. 6. 3| Prevalence of radiographic OA by age B) Women~ ~Determinants,
21 II, 5. 6. 3| progression of radiographic OA (Table 5.6.4). Almost everyone
22 II, 5. 6. 3| 90 years of age will have OA in some joint (Petersson
23 II, 5. 6. 3| and Jacobsson, 2002).~ ~OA is more common in females,
24 II, 5. 6. 3| and progression of knee OA (Petersson and Jacobsson,
25 II, 5. 6. 3| factor for the development of OA of the hand, knee and hip
26 II, 5. 6. 3| about 8.0 for developing OA knee (Davis et al, 1990).
27 II, 5. 6. 3| risk of developing knee OA by 20-30% (Felson, 1996).~ ~
28 II, 5. 6. 3| with development of knee OA. Other mechanical factors
29 II, 5. 6. 3| factors for the development of OA of the knee and hip shown
30 II, 5. 6. 3| greatest relative risk for OA: 4.5 for farming 1-9 years
31 II, 5. 6. 3| particularly among females.~ ~OA was estimated to be the
32 II, 5. 6. 3| available specifically for OA. However in Sweden, osteoarthritis
33 II, 5. 6. 3| care (Levy et al, 1993). OA is a major cause of chronic
34 II, 5. 6. 3| replacement rates, usually for OA, vary in OECD countries
35 II, 5. 6. 3| incidence and prevalence of OA are difficult to predict.
36 II, 5. 6. 3| in greater numbers with OA and greater disability.
37 II, 5. 6. 6| and hand osteoarthritis (OA) in the general population
