Part,  Chapter, Paragraph

  1    I,     2.  3    |              European concern. It is estimated that in the European Union
  2    I,     2.  7    |             the human population, an estimated number of 3.3 billion people,
  3    I,     2. 10.  4|             today is very low: it is estimated that less than 10% of hospitals
  4   II,     4.  1    |           2005 and were collected or estimated to ensure maximum harmonization
  5   II,     4.  1    |          minimum and range of values estimated each year at MS level within
  6   II,     4.  1    |             years in good health, as estimated by the HLY in 2005. Around
  7   II,     5.  1.  1|          Stomach cancer: It has been estimated that most cases of this
  8   II,     5.  2.  4|           Chapter 8).~ ~Table 5.2.7. Estimated prevalence of hypertension
  9   II,     5.  2.  4|            countries.~ ~Table 5.2.8. Estimated mean values of total cholesterol
 10   II,     5.  2.  4|           age ranges.~ ~Table 5.2.9. Estimated prevalence of smoking habit
 11   II,     5.  2.  4|         Chapter 10).~ ~Table 5.2.10. Estimated prevalence of obesity (defined
 12   II,     5.  2.  4|           every inhabited continent, estimated that 22% of heart attacks
 13   II,     5.  3.  1|              cancer sites in EU25 as estimated in 2006.~ ~Table 5.3.1.
 14   II,     5.  3.  1|              in 2006.~ ~Table 5.3.1. Estimated incident cases and deaths
 15   II,     5.  3.  4|          Stomach cancer: It has been estimated that most cases of this
 16   II,     5.  3.  5|            and 1,700,000 deaths were estimated for all cancers all around
 17   II,     5.  3.  5|           rates (Figures 5.3.1) were estimated in Hungary for men (599
 18   II,     5.  3.  5|           rates (Figures 5.3.3) were estimated in Hungary for men (364
 19   II,     5.  3.  5|               standardized incidence estimated rates (European standard)
 20   II,     5.  3.  5|               standardized incidence estimated rates (European standard)
 21   II,     5.  3.  5|               standardized incidence estimated rates (European standard)
 22   II,     5.  3.  5|               standardized incidence estimated rates (European standard)
 23   II,     5.  3.  5|             cases and 118,000 deaths estimated for stomach cancer (Ferlay
 24   II,     5.  3.  5|           rates (Figures 5.3.5) were estimated in Macedonia for men (37
 25   II,     5.  3.  5|           rates (Figures 5.3.7) were estimated in Lithuania for men (29
 26   II,     5.  3.  5|               standardized incidence estimated rates (European standard)
 27   II,     5.  3.  5|               standardized incidence estimated rates (European standard)
 28   II,     5.  3.  5|               standardized incidence estimated rates (European standard)
 29   II,     5.  3.  5|               standardized incidence estimated rates (European standard)
 30   II,     5.  3.  5|              and 207,000 deaths were estimated for colorectal cancer in
 31   II,     5.  3.  5|         maximum incidence rates were estimated in Hungary for men (106
 32   II,     5.  3.  5|          maximum levels of incidence estimated rates (in respect with all
 33   II,     5.  3.  5|               standardized incidence estimated rates (European standard)
 34   II,     5.  3.  5|               standardized incidence estimated rates (European standard)
 35   II,     5.  3.  5|               standardized incidence estimated rates (European standard)
 36   II,     5.  3.  5|               standardized incidence estimated rates (European standard)
 37   II,     5.  3.  5|            000 new cases and 335,000 estimated deaths (Ferlay et al, 2007).
 38   II,     5.  3.  5|           which the female incidence estimated rate was higher than that
 39   II,     5.  3.  5|               standardized incidence estimated rates (European standard)
 40   II,     5.  3.  5|               standardized incidence estimated rates (European standard)
 41   II,     5.  3.  5|               standardized incidence estimated rates (European standard)
 42   II,     5.  3.  5|               standardized incidence estimated rates (European standard)
 43   II,     5.  3.  5|              cancer in women with an estimated 430,000 new cases and 132,
 44   II,     5.  3.  5|           incidence rate in 2006 was estimated in Belgium (138 new cases
 45   II,     5.  3.  5|               standardized incidence estimated rates (European standard)
 46   II,     5.  3.  5|               standardized incidence estimated rates (European standard)
 47   II,     5.  3.  5|               standardized incidence estimated rates (European standard)~
 48   II,     5.  3.  5|         cases and 87,000 deaths were estimated for prostate cancer in Europe (
 49   II,     5.  3.  5|               standardized incidence estimated rates (European standard)
 50   II,     5.  3.  5|               standardized incidence estimated rates (European standard)~
 51   II,     5.  3.  6|      childhood cancers combined were estimated for five regions (West Germany,
 52   II,     5.  3.  6|          childhood cancers were also estimated.~For all childhood cancers
 53   II,     5.  3.  6|             diagnosed in 200002 was estimated.~For all cancers, age-adjusted
 54   II,     5.  4.  1|        worldwide prevalence of 7.5%, estimated to increase up to 8.0% in
 55   II,     5.  4.  1|            with type 2 diabetes were estimated at €2,834 in 1999. The health
 56   II,     5.  4.  2|            measures may be correctly estimated.~Unfortunately, only few
 57   II,     5.  4.  2|            most indicators cannot be estimated using this source.~However,
 58   II,     5.  5.Int|              for more than 7% of all estimated ill-health and premature
 59   II,     5.  5.Int|              of mental ill health is estimated to be equivalent to a reduction
 60   II,     5.  5.Int|        costing the EU27 countries an estimated total of €300 billion every
 61   II,     5.  5.Int|              remains the rule. It is estimated that only around 15% of
 62   II,     5.  5.Int|          epilepsy are declining. The estimated number of children and adolescents
 63   II,     5.  5.  1|           costs from depression were estimated to be euro 118 bn in EU
 64   II,     5.  5.  1|                 Mental disorders are estimated to be undertreated in as
 65   II,     5.  5.  1|              loss of life. One study estimated that economic costs from
 66   II,     5.  5.  1|            of non-fatal self-harm is estimated to be 1040 times more common
 67   II,     5.  5.  1|          percentage of annual change estimated at -6.1%(P<0.0001), –5.4%(
 68   II,     5.  5.  2|      prevalence of dementia in EU is estimated to be 1.1-1.3%, and is constantly
 69   II,     5.  5.  2|      Alzheimer Europe calculated the estimated number of people with dementia
 70   II,     5.  5.  2|        follows:~ ~Table 5.5.2.3. The estimated number of people with dementia
 71   II,     5.  5.  2|           European Union indicate an estimated 5,526,488 to 6,120,842 people
 72   II,     5.  5.  3|          Incidence~Figure 5.5.3.2.1. Estimated prevalence of psychotic
 73   II,     5.  5.  3|             schizophrenia DALY rates estimated from data of 2002 for the
 74   II,     5.  5.  3|        affected by schizophrenia are estimated to be untreated. This may
 75   II,     5.  5.  3|           Prevalence rates have been estimated in different European countries
 76   II,     5.  5.  3|        drug-related deaths cannot be estimated, as comparative estimates
 77   II,     5.  5.  3|               2001). The Registry is estimated to be 90% complete, and
 78   II,     5.  5.  3|        Pugliatti et al, 2006) and an estimated mean annual incidence rate
 79   II,     5.  5.  3|             a nationwide survey, the estimated prevalence in France is
 80   II,     5.  5.  3|            MS incidence in Europe is estimated to be 4 per 100 000, with
 81   II,     5.  5.  3|            and Figure 5.5.3.5.2. The estimated proportion range for mild
 82   II,     5.  5.  3|             society. A recent review estimated costs due to PD resulting
 83   II,     5.  5.  3|            burden of brain disorders estimated the number of PD patients
 84   II,     5.  5.  3|         community (Figure 5.5.3.6.1. Estimated total number of cases of
 85   II,     5.  5.  3|           Europe~ ~Figure 5.5.3.6.1. Estimated total number of cases of
 86   II,     5.  5.  3|              70 and 90 years of age.~Estimated prevalence and incidence
 87   II,     5.  5.  3|     ascertainment may also influence estimated rates (Anderson et al, 1998);
 88   II,     5.  5.  3|         studies. Baldareschi, et al, estimated an average annual incidence
 89   II,     5.  5.  3|        European Brain Council (ECB), estimated the costs of brain disorders
 90   II,     5.  5.  3|             The total cost of PD was estimated at €10.7 billion in 2004
 91   II,     5.  5.  3|              of the healthcare cost, estimated at €1.9 billion. However,
 92   II,     5.  5.  3|    individuals suffering from PD was estimated for Western Europe's 5 most
 93   II,     5.  6.  3|        condition has repeatedly been estimated to be 4-5% of the adult
 94   II,     5.  6.  3|             of a new case. It can be estimated by the number presenting
 95   II,     5.  6.  3|            joints involved and it is estimated in the Global Burden of
 96   II,     5.  6.  3|            Davis et al, 1990). It is estimated that a decrease of 2 BMI
 97   II,     5.  6.  3|              among females.~ ~OA was estimated to be the 5th leading cause
 98   II,     5.  6.  3|           Sweden, osteoarthritis was estimated to incur SEK 7.4 billion (
 99   II,     5.  6.  3|               Merx et al, 2003). The estimated requirement for knee replacement
100   II,     5.  6.  3|     disability. It has been recently estimated that, with current management
101   II,     5.  6.  3|         Table 5.6.7).~ ~Table 5.6.7. Estimated lifetime risks of fractures
102   II,     5.  6.  3|                In Europe it has been estimated that in 2000 there were
103   II,     5.  6.  3|             also in the USA.~ ~It is estimated that around 23% of women
104   II,     5.  6.  3|             5.6.10).~ ~Table 5.6.10. Estimated 10 year risks of fractures
105   II,     5.  6.  4|             active population can be estimated based upon register data
106   II,     5.  6.  4|            of complaints, and can be estimated from sick leave or worker’
107   II,     5.  7.  1|            patients. In 2001, it was estimated that in Italy 1.8% of the
108   II,     5.  7.  3|            the fact that the GFR, as estimated by the MDRD equation (Levey
109   II,     5.  7.  3|            the fact that the GFR, as estimated by the MDRD equation (Levey
110   II,     5.  8.  1|             total deaths and is also estimated to be the seventh cause
111   II,     5.  8.  3|  meta-analysis (Halbert et al, 2006) estimated a prevalence of 9.2% using
112   II,     5.  8.  3|           nearly 5 000 patients, has estimated that the prevalence of COPD
113   II,     5.  8.  3|           the prevalence of COPD was estimated to increase by 40% in males
114   II,     5.  8.  3|             at stage I or higher was estimated at 26.1%, regardless of
115   II,     5.  8.  3|          Murray and Lopez, 1997) has estimated that COPD, which was the
116   II,     5.  8.  3|            of every COPD patient was estimated at 4,366 euro per year:
117   II,     5.  8.  3|          COPD patients in France was estimated at 3.5 billion euro, accounting
118   II,     5.  8.  3|        direct costs per patient were estimated to be 909€ in Spain (Masa
119   II,     5.  9. FB|          allergic diseases and it is estimated that,~by 2015, one out of
120   II,     5.  9. FB|             people across Europe are estimated to suffer from a form of
121   II,     5.  9.  1|           Skoner, 2001).~ ~Asthma is estimated to affect approximately
122   II,     5.  9.  1|       general population while AR is estimated to affect 1030%. Asthma
123   II,     5.  9.  3|             Deaths due to asthma are estimated to be 250,000 per year worldwide.
124   II,     5.  9.  3|              adequate data, they are estimated - in terms of health care
125   II,     5.  9.  4|         professional sensitizers are estimated to determine about 1 in
126   II,     5.  9.  4|          tests increased the overall estimated prevalence by only 1% (
127   II,     5. 10.  1|               which has been roughly estimated around 1-3% in adults and
128   II,     5. 10.  3|              Europe has been roughly estimated to be around 4-6 % in children
129   II,     5. 11.  3|            of skin diseases has been estimated to be as high as 3000, not
130   II,     5. 11.  3|        Writing Group, 2008).~ ~It is estimated that between 10% and 15%
131   II,     5. 11.  3|           exposure to the sun. It is estimated that in 2000 there were
132   II,     5. 11.  3|           melanoma. In Europe, it is estimated that in 2000 there were
133   II,     5. 12.  2|              increase/decrease). The estimated annual percent change (APC)
134   II,     5. 13    |          Branca et al, 2007b). It is estimated that in the EU, obesity
135   II,     5. 13    |            members before 2004) were estimated to be €32.8 billion per
136   II,     5. 15.  1|             on the definition, it is estimated that there are between 5
137   II,     5. 15.  3|             95% of the patients. The estimated numbers have to be validated
138   II,     6.  3.  1|      communicable diseases have been estimated at around 5.3 billion €,
139   II,     6.  3.  1|         study in the Netherlands has estimated annual costs based on both
140   II,     6.  3.  2|           the EU25 every year can be estimated at 3 000 000, and approximately
141   II,     6.  3.  3|            and central Europe, it is estimated that 720 000 people were
142   II,     6.  3.  3|           tools and policies~ ~It is estimated that 30% of the people living
143   II,     7.  3.  2|              this time period. It is estimated that almost 100 000 lives
144   II,     7.  3.  3|              8 days, adding up to an estimated total of € 1.5 billion alone
145   II,     7.  3.  4|       statistics. Their scope can be estimated by considering all unintentional
146   II,     7.  4.  1|           toll for this age group is estimated as 26000 cases in the EU27.
147   II,     7.  4.  1|         departments. This means that estimated 21 million children and
148   II,     8.  1.  3|      self-reported conditions, it is estimated that about 16% of men and
149   II,     8.  2.  2|              EUGLOREH countries, was estimated with the application of
150   II,     8.  2.  2|              EUGLOREH countries, was estimated with the application of
151   II,     8.  2.  3|      impairment (26-40dBHL) has been estimated, it has been assumed to
152   II,     8.  2.  3|             the better ear) has been estimated as 0.1% in a study carried
153   II,     8.  2.  3|            group 15-19 year has been estimated to be 0.1 to 0.2%.~ ~Table
154   II,     8.  2.  3|              1 to 0.2%.~ ~Table 8.5. Estimated prevalence of adult onset
155   II,     8.  2.  3|      prevalence and hearing loss was estimated to be 3.3% (males) and 2.
156   II,     8.  2.  3|             to hearing loss has been estimated to amount, in 2001, to 4.
157   II,     9.  1    |         European Union. Of these, an estimated 25 000 are stillborn and
158   II,     9.  3.  1|           2003). These accidents are estimated to cost the EU about 20
159   II,     9.  3.  1|              for more than 7% of all estimated ill-health and premature
160   II,     9.  3.  1|              of mental ill health is estimated to be equivalent to a reduction
161   II,     9.  3.  1|              remains the norm. It is estimated that only around 15% of
162   II,     9.  3.  1|              in the expanded EU. The estimated number of people in Europe
163   II,     9.  3.  1|        million people in the EU were estimated to be living with diabetes.
164   II,     9.  3.  1|           WHO European Region; it is estimated that there will be 150 million
165   II,     9.  3.  1|    implicated. Moreover, it has been estimated that between 50 and 70%
166   II,     9.  3.  1|          arthritis/rheumatism. It is estimated that rheumatoid arthritis
167   II,     9.  3.  1|             wider European region is estimated to be between 0.1 and 3.
168   II,     9.  4.  3|            Eyesight/blindness: It is estimated that over one million people
169   II,     9.  5.  3|             interview, there were an estimated 12.9 million incidents of
170   II,     9.  5.  3|        intimate partner violence was estimated at £5.7 billion (Euro 8.
171   II,     9.  5.  3|             in their lives and it is estimated that there are 84 million
172   II,     9.  5.  3|          systems, as it is currently estimated that European countries
173  III,    10.  1    |             categories. Globally, an estimated 24% of the disease burden (
174  III,    10.  1    |              life years lost) and an estimated 23% of all deaths (premature
175  III,    10.  2.  1|            in developed countries is estimated directly from national vital
176  III,    10.  2.  1|       sources and methodology.~ ~The estimated data for the prevalence
177  III,    10.  2.  1|          cancer, COPD and CVD. It is estimated that 79,500 people die each
178  III,    10.  2.  1| cerebrovascular disease. The WHO has estimated that in 2000, non-communicable
179  III,    10.  2.  1|             vulnerable target. It is estimated that within a few decades,
180  III,    10.  2.  1|          European Union, it has been estimated that alcohol is related
181  III,    10.  2.  1|   visuospatial skills.~ ~It has been estimated that each year in the European
182  III,    10.  2.  1|          social cost, which has been estimated to be €125 billion each
183  III,    10.  2.  1|              basis of the customer’s estimated blood alcohol concentration (
184  III,    10.  2.  1|          currently increasing. It is estimated, that one million current
185  III,    10.  2.  1|              were reported and it is estimated that there are between 100
186  III,    10.  2.  1|          amphetamines’.It is usually estimated as yearly prevalence rate
187  III,    10.  2.  1|       problem drug users it has been estimated that, in the EU, there might
188  III,    10.  2.  1|          lives.~ ~Figure 10.2.1.3.6. Estimated HCV antibody prevalence
189  III,    10.  2.  1|         individuals. In 2005, it was estimated that at least 580 000 opioid
190  III,    10.  2.  1|    substitution cases in the EU were estimated to be around 73 000 (Farrell,
191  III,    10.  2.  1|              report 2002 (WHO, 2002) estimated that insufficient physical activity
192  III,    10.  2.  1|      Commission, 2000a). It has been estimated that at least half of these
193  III,    10.  2.  1|          Branca et al, 2007b). It is estimated that in the EU, obesity
194  III,    10.  2.  1|            members before 2004) were estimated to be €32.8 billion per
195  III,    10.  2.  1|         change in the prevalence was estimated by taking the difference
196  III,    10.  2.  1|            in health in Slovenia, I: estimated prevalence of selected cardiovascular
197  III,    10.  3.  1|             Dutch Health Council has estimated that in the Netherlands,
198  III,    10.  3.  1|                 Several studies have estimated the burden of disease due
199  III,    10.  3.  1|          Figure 8.1.1.2. It was also estimated that 3.2% of the myocardial
200  III,    10.  3.  2|              of Chemicals (REACH) is estimated to result in benefits 2
201  III,    10.  3.  4|              million people, with an estimated economic damage of more
202  III,    10.  3.  4|              consistent conclusions. Estimated total damages of a 100-year
203  III,    10.  3.  4|           the EU, mortality has been estimated to increase 14% for each
204  III,    10.  3.  4|              20 lives and leaving an estimated 10 000 people homeless.
205  III,    10.  3.  4|            Damage to the economy was estimated to be about US$ 624 million,
206  III,    10.  3.  4|           contributed heavily to the estimated 30% reduction in gross primary
207  III,    10.  3.  4|          production costs, led to an estimated damage of more than 11 billion
208  III,    10.  4.  1|             here below describes the estimated health damage due to PM2.
209  III,    10.  4.  1|              2020.~ ~Table 10.4.1.2. Estimated health damage due to PM2.
210  III,    10.  4.  1|             levels in Europe are now estimated to reduce the statistical
211  III,    10.  4.  1|       traffic accidents. The highest estimated damage to health occurs
212  III,    10.  4.  1|           effects.~ ~The WHO earlier estimated that particulate matter
213  III,    10.  4.  1|              the EU in 2000 has been estimated by the CAFE programme in
214  III,    10.  4.  1|              years lost (VOLY).~This estimated cost of non-action has to
215  III,    10.  4.  1|            20%. The societal cost is estimated at 3 billion Euro/year.
216  III,    10.  4.  2|             to benzo(a)pyrene;~it is estimated that the~carcinogenic potential
217  III,    10.  4.  2|     principle, it cannot be reliably estimated at present, how high the
218  III,    10.  4.  2|              of the magnitude of the estimated figure. The Opinion gave
219  III,    10.  4.  2|            pesticides, the PPR Panel estimated that in all scenarios over
220  III,    10.  4.  2|            the compound from food is estimated; and~· finally, the risk
221  III,    10.  4.  3|              in drinking water . The estimated cancer risk at this level
222  III,    10.  4.  3|             At European level, it is estimated that as many as 50 million
223  III,    10.  4.  5|              been raised so that the estimated health risk to bathers is
224  III,    10.  4.  5|             polluting activities are estimated to have occurred in nearly
225  III,    10.  4.  5|      generation in the EU-25+EFTA is estimated at between 1 750 and 1 900
226  III,    10.  4.  5|           Asia (EECCA) countries are estimated to generate about 3 450
227  III,    10.  4.  5|                the SEE countries are estimated to have an average waste
228  III,    10.  4.  5|          small compared to the total estimated costs. Annual expenditure
229  III,    10.  4.  5|             average about 2 % of the estimated overall management costs
230  III,    10.  4.  5|      reductions in landfill, with an estimated 25 million tonnes of waste
231  III,    10.  5.  1|        European EXPOLIS study, it is estimated that in homes without special
232  III,    10.  5.  1|           Within EU countries, it is estimated that roughly half of these
233  III,    10.  5.  1|              in urban areas.~ ~It is estimated that as many as 50 million
234  III,    10.  5.  1|           communicable diseases. The estimated population across the EU
235  III,    10.  5.  1|             number of studies, it is estimated that the life expectancy
236  III,    10.  5.  1|              in the EU, there are an estimated 80 millions of citizens
237  III,    10.  5.  3|         burden of CVD in the EU25 is estimated to amount to €169 billion
238  III,    10.  5.  3|              CVD mortality. This was estimated to cost about €24.4 billion.
239  III,    10.  5.  3|          costs for the year 2004 was estimated at €240 billion in Europe.
240   IV,    11.  1.  6|              improve, and there were estimated financial savings. In Italy,
241   IV,    11.  6.  2|     International Annual Report 2000 estimated that approximately 25% of
242   IV,    11.  6.  3|            Eastern Europe, it can be estimated that health financing in
243   IV,    12.  2    |              basis of the customer’s estimated blood alcohol concentration (
244   IV,    12. 10    |          below the national per year estimated limits of poverty.~o Law
245   IV,    12. 10    |       consumption~Total consumption (estimated and self-reported)~ ~Mortality
246   IV,    13.  2.  2|         lower-income countries, i.e: estimated to be 2-6% of the total
247   IV,    13.  2.  2|              Health Report 2002 also estimated that over 3% of all disease
248   IV,    13.  2.  3|            reference year 2000) were estimated as follows: 13.2% of total
249   IV,    13.  2.  3|      Worldwide, these fractions were estimated to be 4.1%, 4.4%, 2.8%,
250   IV,    13.  2.  3|            societies.~ ~Globally, an estimated 24% of the disease burden (
251   IV,    13.  2.  3|              life years lost) and an estimated 23% of all premature mortality