in the transplantation field
Current situation of the research in the
transplant field at European level:
The EU should
finance projects that really include most of the European countries, in such a
way that the economic efforts are centred on a lower number of projects but of
a stronger potential impact, related to transplantation medicine both in terms
of biomedical science and public health policy. The role of the EU should be to
facilitate cross-talk between healthcare professionals and politics at
organizational level, i.e. institute a framework for resolution of practical
problems, where ideologies, religion, political influences be abandoned in
favour of pragmatism.
Within the EU
there are huge differences in access that cannot merely be explained by
differences in donation rates. Accessibility means to work hard on organ
shortage, but also set up transparent healthcare processes, expand these
processes to all social classes and racial categories as well as constantly
monitor organ allocation modalities. Again, these goals are to be achieved only
through active integration of all the actors involved in the transplant
process: healthcare professionals, stakeholders
In fact, the Seven Framework Research Programme, recently launched by the
European Commission offers a unique opportunity to implement a new vision of
transplantation research requiring a high level of integration within
published on Transplant International written by Michel Goldman e Kathryn Wood
(Goldman and Wood, 2007) shows the current situation of research at European
level. The two researchers are respectively coordinator and president of the
scientific committee of the project called TRIE (Transplantation Research
Integration across Europe) funded by the European Commission within the 6th
Framework Programme, second last as Specific Support Action. In the last 10
years, many scientists have gone abroad, weakening considerably the European
position in the transplant field; therefore, the European Commission decided to
fund projects aimed at completing the current know-how and the available
resources with new research programmes in the field, and identify priorities in
order to start collaborative research activities at European level. TRIE is one
of these project. It focuses to identify common issues in organ and cell
transplant in order to join forces for a common goal. The project will gather
comments and proposals of the participants and will provide to the European
Commission tools and directions to be taken to improve the research on three
aspects considered as priority by the experts:
biomarkers to define
the risk of rejection and to finalize per and post hematopoietic stem cells
(CSE) and solid organ transplant therapies,
new cell therapies for
CSE and solid organ transplant,
programmes for doctor, surgeons, scientists and for the whole staff involved in
the transplant and research in
the field of CSE and solid organ.
depends on the mobilisation of the European transplant community. To examine
the project and actively participate, please see the dedicated website (www.transplantation-research.eu).
European research project in transplantation
ETPOD is a
project funded by the DG SANCO of the European Commission. The aim of this
project is to design and validate a professional European Training Program on
Organ Donation (ETPOD) at different involvement levels, in order to contribute
to an increase in organ donation knowledge, maximize the impact in the growth
of organ donation rates and disseminate reliable information to the health
community in order to raise donation consciousness and encourage a positive
attitude towards this issue.
Its goals are:
build a solid European collaborative partnership in the organ
donation-transplantation process that will enable to respond to the growing
demand of organ replacement therapy by increasing donation rates.
train Health Care Professionals from the European Union countries with the aim
of providing them with the know-how, competences and motivation in the organ
donation process, to grow to be Transplant Coordinators and lead organ
donation-procurement programs in an efficient and successful way. To design and
validate a professional European Training Program On Organ Donation (ETPOD) at
different involvement levels
Alliance-O (European Group for Coordination
of National Research Programmes on Organ Donation and Transplantation):
consortium is built on already existing collaborations. The group then decided
to focus on organ transplantation policies and planned to apply for an ERA-NET.
The objective is to set up cooperation and coordination of national and
regional research activity through a network of programs in the field of OT.
programmes for improving Organ Transplantation efficiency addressed in this
action are: expanding donor pool (heart beating and non heart beating deceased
donors, living donors), improving the efficiency and equity of allocation
rules, the safety and quality of organ transplantation, the evaluation
methodology and fundamental research.
member states partners : De, Fr, It, Hu, Sp, Po, UK, all represented by
national public bodies involved in the organisation of organ transplantation.
Duration: : 3 years.
Agence de la biomédecine (ex-Etablissement français des Greffes) is the
coordinator of the project.
is a coordination action of the ERA Net scheme of the 6th
Dopki (FP6 SSP-3):
To design specific
tools for establishing the potential for organ donation and its outcome and
define the limits of organ’s safety and quality for improving organ Donation
To create a European
donation and transplant activity registry for delivering information on organs,
tissues and cells to professional operators and institutions taking into
account the EURODONOR project, whose goals are: create protocols, Registry,
implement methodology, deliver information, support institutional bodies.
European Quality System for Tissue
Banking:(Public Health 2003)
To Develop the method
to ensure standards of quality and safety in relation to tissue banking
activities required by the future European Directive.
(Public Health 2005)
documents (Eu./non-Eu Countries), set of practical guidelines of tissues
establishments, training courses for 40 inspectors, system of adverse event
classification and reporting