Part, Chapter, Paragraph

 1 I, 1,1    |          have settled on the use of pigs as a potential source animals
 2 I, 2,2    |            production of transgenic pigs expressing hDAF might provide
 3 I, 2,2    |            produced such transgenic pigs and have demonstrated that
 4 I, 2,2    | demonstrated that organs from these pigs usually do not undergo hyperacute
 5 I, 2,2    |          transgenic hDAF-expressing pigs, it appears that hyperacute
 6 I, 2,2    |          expression of "a-gal" from pigs by knocking out the 1,3
 7 I, 2,2(18)|            generation of transgenic pigs as potential organ donors
 8 I, 2,2(18)|   xenografts from triple-transgenic pigs are not hyperacutely rejected
 9 I, 2,2(18)|            transfer:  production of pigs transgenic for a human regulator
10 I, 2,2    |            yet been accomplished in pigs, although present-day cloning
11 I, 2,3    |            today remains transgenic pigs expressing hDAF (32) and,
12 I, 2,3    |            the second is to produce pigs that express additional
13 I, 2,4    |       measures include the birth of pigs by hysterotomy (caesarean
14 I, 2,4    |           and routine monitoring of pigs and their handlers. These
15 I, 2,4    |        which causes no pathology in pigs but which may cause disease
16 I, 2,4    |            other mammalian species, pigs have sequences in their
17 I, 2,4(41)|            endogenous retrovirus of pigs. Nature Med 3: 282-286. ~
18 I, 2,4    |     Certainly, the elimination from pigs of all PERV, which represents
19 I, 2,5    |             to producing transgenic pigs that express human genes
20 I, 2,5    |          have led to the cloning of pigs,(43) allowing for simple
21 I, 2,5(43)|         Vaught T.D., et al., Cloned pigs produced by nuclear transfer