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1 Intro, 0,0(1)| The potential supply of organ donors; an assessment of
2 Intro, 0,0(1)| assessment of the efficacy of organ procurement efforts in the
3 I, 1,1 | prolong survival of the organ. The most striking success
4 I, 1,1 | survival time for a pig organ in a non-human primate receiving
5 I, 1,1(9) | al., The Pig as Potential Organ Donor for Man. In: Cooper
6 I, 2,2 | Rejection: Immunology of Organ Xenografting ~2. There are
7 I, 2,2 | for achieving successful organ xenotransplantation from
8 I, 2,2 | cells of the source animal organ. Second, acute vascular
9 I, 2,2 | endothelial cells of the source organ. Endothelial cell activation
10 I, 2,2 | coagulation cascade) resulting in organ rejection. Third, the xenograft
11 I, 2,2 | immediately-vascularized organ. Pre-existing xenoreactive
12 I, 2,2 | endothelial cells of the pig organ.(13) These antibodies are
13 I, 2,2 | therapy in the field of organ transplantation. ~Another
14 I, 2,2(18) | transgenic pigs as potential organ donors for humans, Nature
15 I, 2,2(18) | of xenogenic hyperacute organ rejection, Proc Natl Acad
16 I, 2,2(20) | xenograft rejection, Opin Organ Transplant 1999 4: 80-
17 I, 2,2 | immunosuppression leads to organ survival for a far greater
18 I, 2,2(24) | rejection, Current Opinion in Organ Transplantation 1999, 4:
19 I, 2,3 | lead to rejection of the organ.(27) Transplantation of
20 I, 2,3(27) | xenograft rejection, Opin Organ Transplant 1999 4: 80-8;
21 I, 2,3 | rejection of a hamster organ transplanted to a rat appear
22 I, 2,3 | vascular rejection of a pig organ in a non-human primate in
23 I, 2,3 | refers to the survival of an organ in the presence of anti-graft
24 I, 2,3 | accommodation is that the surviving organ expresses genes in its endothelium
25 I, 2,3 | muscle cells that protect the organ from rejection.(30) To what
26 I, 2,3 | therapeutically to aid pig organ survival in primates is
27 I, 2,4 | would presumably occur in an organ were it successfully transplanted
28 I, 3,6 | clinical trials with solid organ transplants. Porcine pancreatic
29 I, 3,6 | opinion as to how long a pig organ should survive in a non-human
30 I, 3,6 | clinical trials using solid organ xenografts are warranted. ~
31 I, 3,6 | a permanent replacement organ, the option of using pig
32 II, 1 | subjective impact that an organ or tissue of animal origin
33 II, 1,9 | acceptability of an animal organ, - once it has been established
34 II, 1,10 | introduction of a foreign organ into the human body modifies
35 II, 1,10 | implantation of a foreign organ into a human body finds
36 II, 1,11(61) | subject insofar as it is the organ representing the "principal
37 II, 1,12 | condition that "the transplanted organ does not affect the psychological
38 II, 2,12(64) | Look at Animal-to-Human Organ Transplantation, Kennedy
39 II, 2,14 | acceptance of a foreign organ,(68) especially when it
40 II, 2,14(69) | Psychiatric Aspects of Organ Transplantation, New York:
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