Part, Chapter, Paragraph

 1 I, 1,1    |          also been attempted using pig hearts (three cases) or
 2 I, 1,1    | improvement in survival time for a pig organ in a non-human primate
 3 I, 1,1(9) |           Rolf J.L.L., et al., The Pig as Potential Organ Donor
 4 I, 1,1(10)|        survival of HDAF transgenic pig hearts transplanted into
 5 I, 1,1(10)|            A human CD46 transgenic pig model system for the study
 6 I, 2,2    |           xenotransplantation from pig to primate (human and non-human).
 7 I, 2,2    |           endothelial cells of the pig organ.(13) These antibodies
 8 I, 2,2    |             GlcNac antigens of the pig, also known as "a-gal".(14)
 9 I, 2,2(15)|         and antibody adsorption on pig cardiac xenograft survival
10 I, 2,2    |    introduced into the membrane of pig endothelial cells. The molecule
11 I, 2,2    |            presence of hDAF in the pig endothelial cells prevented
12 I, 2,2    |            hyperacute rejection of pig organs transplanted into
13 I, 2,2(18)|            A human CD46 transgenic pig model system for the study
14 I, 2,2(18)|          inhibitor in a transgenic pig as a model for the prevention
15 I, 2,2    |         system of the recipient to pig antigens without immunosuppression).(25)
16 I, 2,3    |            vascular rejection of a pig organ in a non-human primate
17 I, 2,3    |        used therapeutically to aid pig organ survival in primates
18 I, 2,3    |    survival. In most cases, normal pig organs are rejected hyperacutely
19 I, 2,3    |            rapidly than transgenic pig organs expressing hDAF.(33)
20 I, 2,3(33)|            hyperacute rejection of pig organs. In:  Cooper D.K.
21 I, 2,3    |            delayed.(34) Transgenic pig hearts have been shown to
22 I, 2,3(34)|        survival of HDAF transgenic pig hearts transplanted into
23 I, 2,3(35)|        survival of HDAF transgenic pig hearts transplanted into
24 I, 2,3    |         longer survival periods of pig organs in primates. The
25 I, 2,4    |         and colleagues showed that pig retroviruses could infect
26 I, 2,4    |         patients exposed to living pig tissues was studied for
27 I, 2,4    |           PERV infection, although pig cells containing retroviral
28 I, 2,4    |        years after exposure to the pig tissue. It is a matter open
29 I, 2,4    |           in any event to very few pig cells, as compared with
30 I, 2,4(42)|       patients treated with living pig tissue. Science 285: 1236-
31 I, 2,5    |     introduced into the DNA of the pig genome during the cloning
32 I, 2,5(43)|      Iwamoto M., Akita T., et al., Pig cloning by microinjection
33 I, 3,6    |          multicentre studies using pig hepatocytes in artificial
34 I, 3,6    |           opinion as to how long a pig organ should survive in
35 I, 3,6    |   involving the transplantation of pig organs into humans. Some
36 I, 3,6    |        more have been obtained for pig organs which are transplanted
37 I, 3,6    |         However, while survival of pig organs in non-human primates
38 I, 3,6    |         organ, the option of using pig organs as "bridge' transplants
39 I, 3,6(49)|        survival of HDAF transgenic pig hearts transplanted into